2332897-85-3

Nav1.1 activator 1 Chemical Structure
2332897-85-3

Chemical Structure

Nav1.1 activator 1

  • CAS No.: 2332897-85-3
  • Formula:C24H23F3N4O
  • Molecular Weight:440.46

IUPAC Name: (S)-4-(2,5-difluorophenyl)-2-(3-fluoropyrrolidin-1-yl)-N-(6-isopropylpyridin-3-yl)nicotinamide

InChIKey: HRGJTEFGFUJXIF-INIZCTEOSA-N

SMILES: O=C(C1=C(C2=CC(F)=CC=C2F)C=CN=C1N3C[C@@H](F)CC3)NC4=CC=C(C(C)C)N=C4

Biological Activity: Nav1.1 activator 1 (compound 4), a highly potent Nav1.1 activator with BBB penetration, increases decay time constant (tau) of Nav1.1 currents at 0.03 μM along with significant selectivity against Nav1.2, Nav1.5, and Nav1.6[1].

Cat. No. Product Name Purity Description Pricing
HY-126429 		Nav1.1 activator 1 98.98% Nav1.1 activator 1 (compound 4), a highly potent Nav1.1 activator with BBB penetration, increases decay time constant (tau) of Nav1.1 currents at 0.03 μM along with significant selectivity against Nav1.2, Nav1.5, and Nav1.6.
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