2338811-71-3
2338811-71-3
Chemical Structure
CTP Synthetase-IN-1
- CAS No.: 2338811-71-3
- Formula:C20H19F3N6O3S2
- Molecular Weight:512.53
IUPAC Name: 2-(2-(cyclopropanesulfonamido)thiazol-4-yl)-2-methyl-N-(5-(6-(trifluoromethyl)pyrazin-2-yl)pyridin-2-yl)propanamide
InChIKey: CZIDGRDZSFIUHX-UHFFFAOYSA-N
SMILES: O=C(C(C)(C)C1=CSC(NS(=O)(C2CC2)=O)=N1)NC3=NC=C(C4=NC(C(F)(F)F)=CN=C4)C=C3
Biological Activity: CTP Synthetase-IN-1 is a potent, orally active cytidine 5'-triphosphate synthetase (CTPS) inhibitor with IC50s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively. CTP Synthetase-IN-1 has anti-inflammatory effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CTP Synthetase-IN-1 | 99.70% | CTP Synthetase-IN-1 is a potent, orally active cytidine 5'-triphosphate synthetase (CTPS) inhibitor with IC50s of 32 nM and 18 nM for human CTPS1 and human CTPS2, respectively. CTP Synthetase-IN-1 has anti-inflammatory effects. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.56
HY-157746CTPS1-IN-1 -
Similarity Score 0.55
HY-157783Dencatistat -
Similarity Score 0.48
HY-153855Zamaporvint -
Similarity Score 0.46
HY-112701CCR6 inhibitor 1 -
Similarity Score 0.46
HY-168267XH161-180 -
Similarity Score 0.44
HY-156551Porcn-IN-2 -
Similarity Score 0.44
HY-147083SGC-AAK1-1N -
Similarity Score 0.44
HY-144652IDO1-IN-19 -
Similarity Score 0.44
HY-17545LGK974 -
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