2341841-07-2
Chemical Structure
JMS-17-2 hydrochloride
- CAS No.: 2341841-07-2
- Formula:C25H27Cl2N3O
- Molecular Weight:456.41
IUPAC Name: 5-(3-(4-(4-chlorophenyl)piperidin-1-yl)propyl)pyrrolo[1,2-a]quinoxalin-4(5H)-one hydrochloride
InChIKey: UAGOSAKAAICKNK-UHFFFAOYSA-N
SMILES: O=C1C2=CC=CN2C3=C(C=CC=C3)N1CCCN4CCC(C5=CC=C(Cl)C=C5)CC4.[H]Cl
Biological Activity: JMS-17-2 hydrochloride is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 hydrochloride impairs metastatic seeding and colonization of breast cancer cells[1].
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JMS-17-2 hydrochloride | JMS-17-2 hydrochloride is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 hydrochloride impairs metastatic seeding and colonization of breast cancer cells. | |||||||||||||||||||||
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Keywords