2361139-70-8
2361139-70-8
Chemical Structure
RIPK3-IN-1
- CAS No.: 2361139-70-8
- Formula:C29H25FN4O4
- Molecular Weight:512.53
IUPAC Name: N-(4-((2-(cyclopropanecarboxamido)pyridin-4-yl)oxy)-2,3-dimethylphenyl)-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide
InChIKey: PETCZXAONWLUFT-UHFFFAOYSA-N
SMILES: O=C(C1=CC=CN(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=CC(NC(C5CC5)=O)=NC=C4)C(C)=C3C
Biological Activity: RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9.1 nM. RIPK3-IN-1 inhibits RIPK1 and RIPK2 with IC50s of 5.5 and >10 μM. RIPK3-IN-1 is also a c-Met kinase inhibitor with an IC50 of 1.1 μM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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RIPK3-IN-1 | 99.30% | RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9.1 nM. RIPK3-IN-1 inhibits RIPK1 and RIPK2 with IC50s of 5.5 and >10 μM. RIPK3-IN-1 is also a c-Met kinase inhibitor with an IC50 of 1.1 μM. | ||||||||||||||||||||
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References
Keywords
