2365417-91-8
Chemical Structure
SiRA 2
- CAS No.: 2365417-91-8
- Formula:C33H42N4O5Si
- Molecular Weight:602.80
InChIKey: VZACMAUVTBSQSR-UHFFFAOYSA-N
SMILES: O=C(C1=C(C(C2=C([Si](C)(C)C3=C/4)C=C(N(C)C)C=C2)=C3C=CC4=[N+](C)\C)C=CC(C(NCCOCCOCCN)=O)=C1)[O-]
Biological Activity: SiRA 2 is a fluorescent inducer with a Kd value of 430 nM for binding to the SiRA RNA aptamer. When used in combination with the SiRA aptamer, SiRA 2 enables live-cell RNA imaging of aptamer-labeled mRNA as well as stimulated emission depletion super-resolution microscopy imaging. SiRA 2 has high photostability and forms a bright far-red light-up aptamer system upon binding to SiRA[1].
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SiRA 2 | SiRA 2 is a fluorescent inducer with a Kd value of 430 nM for binding to the SiRA RNA aptamer. When used in combination with the SiRA aptamer, SiRA 2 enables live-cell RNA imaging of aptamer-labeled mRNA as well as stimulated emission depletion super-resolution microscopy imaging. SiRA 2 has high photostability and forms a bright far-red light-up aptamer system upon binding to SiRA. | |||||||||||||||||||||
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Keywords
