SiRA 2
SiRA 2 is a fluorescent inducer with a Kd value of 430 nM for binding to the SiRA RNA aptamer. When used in combination with the SiRA aptamer, SiRA 2 enables live-cell RNA imaging of aptamer-labeled mRNA as well as stimulated emission depletion super-resolution microscopy imaging. SiRA 2 has high photostability and forms a bright far-red light-up aptamer system upon binding to SiRA.
For research use only. We do not sell to patients.
- CAS No.: 2365417-91-8
- Formula: C33H42N4O5Si
- Molecular Weight:602.80
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
SiRA 2 binds to the 50-nucleotide SiRA RNA aptamer with a nanomolar dissociation constant of 430 nM, showing no loss of affinity compared with the full-length parental aptamer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2365417-91-8
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Molecular Weight 602.80
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Formula C33H42N4O5Si
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SMILES
O=C(C1=C(C(C2=C([Si](C)(C)C3=C/4)C=C(N(C)C)C=C2)=C3C=CC4=[N+](C)\C)C=CC(C(NCCOCCOCCN)=O)=C1)[O-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)