2368945-27-9
2368945-27-9
Chemical Structure
ABBV-712
- CAS No.: 2368945-27-9
- Formula:C24H28N4O5
- Molecular Weight:452.50
InChIKey: GTXKSTKFOCDTPI-DEOSSOPVSA-N
SMILES: CC(NC1=CC2=C(C=N1)N(C=C2C3=NC([C@]4(COCC4)OC)=CC(COC)=C3)C5COC5)=O
Biological Activity: ABBV-712 is a selective and orally active inhibitor of Tyrosine kinase 2 (TYK2). ABBV-712 has EC50 values of 0.01, 0.19, and 0.17 μM for TYK2 JH2, TYK2 cells and human whole blood, respectively. ABBV-712 has anti-inflammatory activity and can be used in the research of autoimmune diseases[1].
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ABBV-712 | 99.94% | ABBV-712 is a selective and orally active inhibitor of Tyrosine kinase 2 (TYK2). ABBV-712 has EC50 values of 0.01, 0.19, and 0.17 μM for TYK2 JH2, TYK2 cells and human whole blood, respectively. ABBV-712 has anti-inflammatory activity and can be used in the research of autoimmune diseases. | ||||||||||||||||||||
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References
Keywords
