2375720-38-8

LH1307 Chemical Structure
2375720-38-8

Chemical Structure

LH1307

  • CAS No.: 2375720-38-8
  • Formula:C54H58N8O6
  • Molecular Weight:915.09

IUPAC Name: N,N'-(((((((2,2'-dimethyl-[1,1'-biphenyl]-3,3'-diyl)bis(methylene))bis(oxy))bis(2-((5-cyanopyridin-3-yl)methoxy)-5-methyl-4,1-phenylene))bis(methylene))bis(azanediyl))bis(ethane-2,1-diyl))diacetamide

InChIKey: RNCINFJGGSQEHN-UHFFFAOYSA-N

SMILES: N#CC1=CN=CC(COC2=CC(OCC3=CC=CC(C4=CC=CC(COC5=C(C)C=C(CNCCNC(C)=O)C(OCC6=CC(C#N)=CN=C6)=C5)=C4C)=C3C)=C(C)C=C2CNCCNC(C)=O)=C1

Biological Activity: LH1307 is a C2-symmetric inhibitor of PD-1/PD-L1 protein-protein interactions with a IC50 value of 3.0 μM and can be used in cancer studies[1].

Cat. No. Product Name Purity Description Pricing
HY-132212
LH1307 96.9% LH1307 is a C2-symmetric inhibitor of PD-1/PD-L1 protein-protein interactions with a IC50 value of 3.0 μM and can be used in cancer studies.
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