2376914-71-3
2376914-71-3
Chemical Structure
SMO-IN-3
- CAS No.: 2376914-71-3
- Formula:C27H25F4N3O2
- Molecular Weight:499.50
IUPAC Name: 4-fluoro-N-methyl-N-(1-(2-(phenylamino)benzoyl)piperidin-4-yl)-2-(trifluoromethyl)benzamide
InChIKey: YHMNCGDXVJEIDT-UHFFFAOYSA-N
SMILES: O=C(N(C)C1CCN(C(C2=CC=CC=C2NC3=CC=CC=C3)=O)CC1)C4=CC=C(F)C=C4C(F)(F)F
Biological Activity: SMO-IN-3 (compound 12a) is a potent smoothened (SMO) inhibitor with an IC50 value of 34.09 nM for hedgehog (Hh) signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].
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SMO-IN-3 | SMO-IN-3 (compound 12a) is a potent smoothened (SMO) inhibitor with an IC50 value of 34.09 nM for hedgehog (Hh) signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity. | |||||||||||||||||||||
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