2379335-06-3
2379335-06-3
Chemical Structure
Anticancer agent 34
- CAS No.: 2379335-06-3
- Formula:C17H14BrN3O3S2
- Molecular Weight:452.35
IUPAC Name: N-((4-(4-bromophenyl)thiazol-2-yl)carbamoyl)-4-methylbenzenesulfonamide
InChIKey: MARSLVWRGVPRLW-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(C)C=C1)(NC(NC2=NC(C3=CC=C(Br)C=C3)=CS2)=O)=O
Biological Activity: Anticancer agent 34 (compound 9), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 34 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/ml. Anticancer agent 34 inhibits A549, PC3 cell growth with IC50s of 8.4 µg/ml, 7.8 µg/ml, respectively[1].
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Anticancer agent 34 | Anticancer agent 34 (compound 9), a sulfonylurea derivative, is a potent antimicrobial and anticancer agent. Anticancer agent 34 inhibits the microbial growth of B. mycoides, E. coli, and C. albicans with a MIC between 0.156 and 0.039 mg/ml. Anticancer agent 34 inhibits A549, PC3 cell growth with IC50s of 8.4 µg/ml, 7.8 µg/ml, respectively. | |||||||||||||||||||||
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