2389016-82-2
2389016-82-2
Chemical Structure
Antiproliferative agent-6
- CAS No.: 2389016-82-2
- Formula:C21H14ClFN6
- Molecular Weight:404.83
IUPAC Name: 5-(4-(3-chloropropyl)-1H-1,2,3-triazol-1-yl)-2-fluorobenzo[4,5]imidazo[1,2-a]quinoline-6-carbonitrile
InChIKey: CHNJNWJESLUCGC-UHFFFAOYSA-N
SMILES: N#CC1=C(C2=C(N3C1=NC4=C3C=CC=C4)C=C(C=C2)F)N5C=C(N=N5)CCCCl
Biological Activity: Antiproliferative agent-6 (compound 8a) is a potent antitumor agent. Antiproliferative agent-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 μM, 2 μM, 0.7 μM and 3.5 μM, respectively[1].
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Antiproliferative agent-6 | Antiproliferative agent-6 (compound 8a) is a potent antitumor agent. Antiproliferative agent-6 has antiproliferative activity against cancer cell lines HCT116, MCF-7, H460 and non-tumor aneuploid immortal keratinocyte HaCaT cells with GI50s of 0.5 μM, 2 μM, 0.7 μM and 3.5 μM, respectively. | |||||||||||||||||||||
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