2393980-27-1
2393980-27-1
Chemical Structure
KUNB106
- CAS No.: 2393980-27-1
- Formula:C27H34N4O3
- Molecular Weight:462.58
InChIKey: XQCMRWDZMVGIFA-UHFFFAOYSA-N
SMILES: CCCC1=CC2=C(C(N3CCC(CC3)O)=CC(N4N=C(C5=C4CC(C)(CC5=O)C)C)=C2)C(N1)=O
Biological Activity: KUNB106 is a selective Hsp90β inhibitor with KDs of 91 nM and 38 μM against Hsp90β and Hsp90α. KUNB106 exhibits antiproliferative activity against MDA-MB-231 cells, A549 and SKOV-3 cells. KUNB106 can be used for the study of triple negative breast cancer[1].
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KUNB106 | KUNB106 is a selective Hsp90β inhibitor with KDs of 91 nM and 38 μM against Hsp90β and Hsp90α. KUNB106 exhibits antiproliferative activity against MDA-MB-231 cells, A549 and SKOV-3 cells. KUNB106 can be used for the study of triple negative breast cancer. | |||||||||||||||||||||
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References
Keywords
