2396664-85-8

FGFR4-IN-11 Chemical Structure
2396664-85-8

Chemical Structure

FGFR4-IN-11

  • CAS No.: 2396664-85-8
  • Formula:C29H29N5O5
  • Molecular Weight:527.57

IUPAC Name: N-(2-((3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl)amino)-5-morpholinophenyl)acrylamide

InChIKey: YMFNEYWPMKYGQY-UHFFFAOYSA-N

SMILES: COC1=CC(C(C2=CNC3=NC(NC4=C(C=C(C=C4)N5CCOCC5)NC(C=C)=O)=CC=C32)=O)=CC(OC)=C1

Biological Activity: FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-147515
FGFR4-IN-11 FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity.
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