1. Protein Tyrosine Kinase/RTK
  2. FGFR
  3. FGFR4-IN-11

FGFR4-IN-11 

Cat. No.: HY-147515
Handling Instructions

FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity.

For research use only. We do not sell to patients.

FGFR4-IN-11 Chemical Structure

FGFR4-IN-11 Chemical Structure

CAS No. : 2396664-85-8

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Description

FGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].

IC50 & Target

FGFR4

2.1 nM (IC50)

Molecular Weight

527.57

Formula

C29H29N5O5

CAS No.
SMILES

COC1=CC(C(C2=CNC3=NC(NC4=C(C=C(C=C4)N5CCOCC5)NC(C=C)=O)=CC=C32)=O)=CC(OC)=C1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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FGFR4-IN-11
Cat. No.:
HY-147515
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