239807-03-5
Chemical Structure
(R,R)-Voriconazole
Synonym(s): (R,R)-UK-109496
- CAS No.: 239807-03-5
- Formula:C16H14F3N5O
- Molecular Weight:349.31
InChIKey: BCEHBSKCWLPMDN-QLJPJBMISA-N
SMILES: C[C@H](C1=NC=NC=C1F)[C@@](O)(C2=C(C=C(C=C2)F)F)CN3C=NC=N3
Biological Activity: (R,R)-Voriconazole ((R,R)-UK-109496) is an enantiomer of Voriconazole (HY-76200). Voriconazole (UK-109496) is a second-generation broad-spectrum triazole antifungal compound that inhibits the biosynthesis of fungal ergosterol. Voriconazole exerts its antifungal activity by inhibiting the 14-α-lanosterol demethylation mediated by fungal cytochrome P450 enzymes. Voriconazole exhibits blood-brain barrier permeability[1].
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(R,R)-Voriconazole | (R,R)-Voriconazole ((R,R)-UK-109496) is an enantiomer of Voriconazole (HY-76200). Voriconazole (UK-109496) is a second-generation broad-spectrum triazole antifungal compound that inhibits the biosynthesis of fungal ergosterol. Voriconazole exerts its antifungal activity by inhibiting the 14-α-lanosterol demethylation mediated by fungal cytochrome P450 enzymes. Voriconazole exhibits blood-brain barrier permeability. | |||||||||||||||||||||
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Keywords
