2408882-54-0
Chemical Structure
BCL6-IN-6
- CAS. Nr.: 2408882-54-0
- Formula:C27H31FN6O2S
- Molecular Weight:522.64
IUPAC Name: 5-(cyclopent-1-en-1-yl)-N-(4-((2-((3R,5S)-3,5-dimethylpiperazin-1-yl)-5-fluoropyrimidin-4-yl)amino)-2-methoxyphenyl)thiophene-2-carboxamide
InChIKey: VJFKSXHAFLCLLP-CALCHBBNSA-N
SMILES: O=C(C1=CC=C(C2=CCCC2)S1)NC3=CC=C(NC4=NC(N5C[C@@H](C)N[C@@H](C)C5)=NC=C4F)C=C3OC
Biological Activity: BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL)[1].
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BCL6-IN-6 | 98.10% | BCL6-IN-6 is a potent inhibitor of transcriptional repressor B-cell lymphoma 6 (BCL6). BCL6-IN-6 significantly blocks the interaction of BCL6 with its corepressors and reactivates BCL6 target genes in a dose-dependent manner. BCL6-IN-6 has the potential for the research of diffuse large B-cell lymphoma (DLBCL). | ||||||||||||||||||||
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