2409959-90-4
2409959-90-4
Chemical Structure
YT 6-2
- CAS No.: 2409959-90-4
- Formula:C25H27F2NO5
- Molecular Weight:459.48
InChIKey: RPRSZJZVWDEXDD-JOCHJYFZSA-N
SMILES: FC(C=C1)=CC=C1COC2=C(C=CC(OC[C@H](O)CNCCO)=C2)OCC3=CC=C(C=C3)F
Biological Activity: YT 6-2 is the p62/SQSTM1 targeting, autophagy-targeting ligand (ATL) of AUTOTAC ATC-324 (HY-169385), which is an bivalent AR (Androgen Receptor) degrader. ATC-324 can reduce nuclear AR levels and downregulate target gene expression of AR and AR-v7, and also has a degradation effect on common AR mutants in PCa[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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YT 6-2 | 98.15% | YT 6-2 is the p62/SQSTM1 targeting, autophagy-targeting ligand (ATL) of AUTOTAC ATC-324 (HY-169385), which is an bivalent AR (Androgen Receptor) degrader. ATC-324 can reduce nuclear AR levels and downregulate target gene expression of AR and AR-v7, and also has a degradation effect on common AR mutants in PCa. | ||||||||||||||||||||
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References
Keywords
