2410075-64-6
2410075-64-6
Chemical Structure
CTSL/CAPN1-IN-2
- CAS No.: 2410075-64-6
- Formula:C34H40N4O6
- Molecular Weight:600.70
InChIKey: SPWWDAZUHUGPIX-QKDODKLFSA-N
SMILES: O=C(C1=CC2=CC=CC=C2O1)N[C@@H](CC3CCCCC3)C(N[C@H](C(C(NCC4=CC=CC=C4)=O)=O)C[C@H]5C(NCCC5)=O)=O
Biological Activity: CTSL/CAPN1-IN-2 (Compound 14b) is an orally active inhibitor of both CTSL and CAPN1, with IC50 values of 6.88 nM and 347.6 nM, respectively. CTSL/CAPN1-IN-2 possesses anti-inflammatory properties and favorable pharmacokinetic characteristics. CTSL/CAPN1-IN-2 exhibits broad-spectrum antiviral activity against coronaviruses by blocking viral entry[1].
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CTSL/CAPN1-IN-2 | CTSL/CAPN1-IN-2 (Compound 14b) is an orally active inhibitor of both CTSL and CAPN1, with IC50 values of 6.88 nM and 347.6 nM, respectively. CTSL/CAPN1-IN-2 possesses anti-inflammatory properties and favorable pharmacokinetic characteristics. CTSL/CAPN1-IN-2 exhibits broad-spectrum antiviral activity against coronaviruses by blocking viral entry. | |||||||||||||||||||||
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References
Keywords
