2410796-79-9
2410796-79-9
Chemical Structure
Sovilnesib
Synonym(s): AMG 650
- CAS No.: 2410796-79-9
- Formula:C26H34F2N6O4S
- Molecular Weight:564.65
IUPAC Name: N-(2-(4,4-difluoropiperidin-1-yl)-6-methylpyrimidin-4-yl)-4-((2-hydroxyethyl)sulfonamido)-2-(6-azaspiro[2.5]octan-6-yl)benzamide
InChIKey: KBDGEJDIHZDPHN-UHFFFAOYSA-N
SMILES: O=C(NC1=NC(N2CCC(F)(F)CC2)=NC(C)=C1)C3=CC=C(NS(=O)(CCO)=O)C=C3N(CC4)CCC54CC5
Biological Activity: Sovilnesib (AMG 650) is a potent, orally active kinesin-like protein KIF18A inhibitor with an IC50 value of 0.071 μM. Sovilnesib can be used for the research of cancer[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sovilnesib | 99.90% | Sovilnesib (AMG 650) is a potent, orally active kinesin-like protein KIF18A inhibitor with an IC50 value of 0.071 μM. Sovilnesib can be used for the research of cancer. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.91
HY-162110AM-9022 -
Similarity Score 0.91
HY-162110A(S)-AM-9022 -
Similarity Score 0.68
HY-144894AM-5308 -
Similarity Score 0.65
HY-162532KIF18A-IN-10 -
Similarity Score 0.65
HY-158757KIF18A-IN-12 -
Similarity Score 0.63
HY-162531KIF18A-IN-9 -
Similarity Score 0.63
HY-162937KIF18A-IN-13 -
Similarity Score 0.62
HY-180170KIF18A-IN-18 -
Similarity Score 0.62
HY-180641KIF18A-IN-19 -
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