2413865-92-4
Chemical Structure
Antibacterial agent 83
- CAS No.: 2413865-92-4
- Formula:C11H5Cl2N3O2
- Molecular Weight:282.08
IUPAC Name: 5-(4,5-dichloro-2-hydroxybenzoyl)-1H-pyrazole-3-carbonitrile
InChIKey: XTPYKTMUWMXBMC-UHFFFAOYSA-N
SMILES: N#CC1=NNC(C(C2=C(C=C(C(Cl)=C2)Cl)O)=O)=C1
Biological Activity: Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes[1].
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Antibacterial agent 83 | Antibacterial agent 83 (compound 17h) displays potent antibacterial activity against various vancomycin-resistant Enterococcus faecalis (VRE) and methicillin-resistant Staphylococcus aureus (MRSA). Antibacterial agent 83 can significantly reduce the biofilm formation of MRSA and exhibited promising selectivity. Antibacterial agent 83 is metabolically stable in human liver microsomes. | |||||||||||||||||||||
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Keywords
