2416138-42-4
2416138-42-4
Chemical Structure
V-9302 hydrochloride
- CAS 番号: 2416138-42-4
- Formula:C34H39ClN2O4
- Molecular Weight:575.14
IUPAC Name: (S)-2-amino-4-(bis(2-((3-methylbenzyl)oxy)benzyl)amino)butanoic acid hydrochloride
InChIKey: LUQMUDMPRZSZTJ-YNMZEGNTSA-N
SMILES: O=C(O)[C@@H](N)CCN(CC1=CC=CC=C1OCC2=CC=CC(C)=C2)CC3=CC=CC=C3OCC4=CC=CC(C)=C4.[H]Cl
Biological Activity: V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells[1].
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V-9302 hydrochloride | 99.10% | V-9302 hydrochloride is a competitive antagonist of transmembrane glutamine flux. V-9302 hydrochloride selectively and potently targets the amino acid transporter ASCT2 (SLC1A5) not ASCT1. V-9302 hydrochloride inhibits ASCT2-mediated glutamine uptake (IC50=9.6 µM) in HEK-293 cells. | ||||||||||||||||||||
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