2418537-98-9
Chemical Structure
Ciprofloxacin prodrug-1
- CAS No.: 2418537-98-9
- Formula:C27H28FN5O7S
- Molecular Weight:585.60
InChIKey: KGEKSIGSXQBXAY-PXDATVDWSA-N
SMILES: O=C(C(N12)=C(COC(C3=CN(C4CC4)C5=C(C=C(F)C(N6CCNCC6)=C5)C3=O)=O)CS[C@]2([H])[C@H](NC(C)=O)C1=O)O
Biological Activity: Ciprofloxacin prodrug-1 (Compound 35) is an activated prodrug of β-lactase. Ciprofloxacin prodrug-1 exhibits good antibacterial activity against bacteria containing β-lactase (MIC = 63 nM). After being hydrolyzed by β-lactase, Ciprofloxacin prodrug-1 can release Ciprofloxacin (HY-B0356), thereby inhibiting the activity of DNA gyrase. Ciprofloxacin prodrug-1 can be used to study infections caused by enzyme-producing drug-resistant bacteria (such as uropathogenic Escherichia coli)[1].
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Ciprofloxacin prodrug-1 | Ciprofloxacin prodrug-1 (Compound 35) is an activated prodrug of β-lactase. Ciprofloxacin prodrug-1 exhibits good antibacterial activity against bacteria containing β-lactase (MIC = 63 nM). After being hydrolyzed by β-lactase, Ciprofloxacin prodrug-1 can release Ciprofloxacin (HY-B0356), thereby inhibiting the activity of DNA gyrase. Ciprofloxacin prodrug-1 can be used to study infections caused by enzyme-producing drug-resistant bacteria (such as uropathogenic Escherichia coli). | |||||||||||||||||||||
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