2420449-92-7
Chemical Structure
IOPBA
- CAS No.: 2420449-92-7
- Formula:C29H21BN4O3
- Molecular Weight:484.31
InChIKey: HVEAONBSIQDSKG-UHFFFAOYSA-N
SMILES: OB(C1=CC=C(C=C1)C2=NC(C3=CC=C(C=C3)C4=NC(C5=CC=CC=C5)=C(N4)C6=CC=CC=C6)=NO2)O
Biological Activity: IOPBA is a fluorescent probe that can be used for the detection and bioimaging of trivalent iron ions Fe3+ and fluoride ions F- in living cells. IOPBA emits blue fluorescence in its native state, but upon the introduction of Fe3+, it forms a Fe3+-IOPBA π-complex, where Fe3+ ions coordinate with two phenyl groups of IOPBA, resulting in fluorescence quenching. IOPBA returns to its free state and recovers its original fluorescence after F- sequesters Fe3+ to form the more stable [FeF6]3- and dissociates the Fe3+-IOPBA complex. The excitation wavelength of IOPBA is 342 nm, and its emission wavelength is 458 nm[1].
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IOPBA | IOPBA is a fluorescent probe that can be used for the detection and bioimaging of trivalent iron ions Fe3+ and fluoride ions F- in living cells. IOPBA emits blue fluorescence in its native state, but upon the introduction of Fe3+, it forms a Fe3+-IOPBA π-complex, where Fe3+ ions coordinate with two phenyl groups of IOPBA, resulting in fluorescence quenching. IOPBA returns to its free state and recovers its original fluorescence after F- sequesters Fe3+ to form the more stable [FeF6]3- and dissociates the Fe3+-IOPBA complex. The excitation wavelength of IOPBA is 342 nm, and its emission wavelength is 458 nm. | |||||||||||||||||||||
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