2438125-72-3
2438125-72-3
Chemical Structure
ALV-05-077-01
- CAS No.: 2438125-72-3
- Formula:C25H21F3N4O5
- Molecular Weight:514.45
SMILES: O=C1C=C(C(N1C2C(NC(CC2)=O)=O)=O)NC3=CC=CC(CCC(NC4=CC=CC(C(F)(F)F)=C4)=O)=C3
Biological Activity: ALV-05-077-01 is a BLC6/BLC6B degrader. ALV-05-077-01 depletes endogenous BCL6 levels in SuDHL4 cells (high BCL6 expression) and BCL6B levels in KYO1 cells (high BCL6B expression). ALV-05-077-01 can be used for the study of hematological malignancies[1].
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ALV-05-077-01 | ALV-05-077-01 is a BLC6/BLC6B degrader. ALV-05-077-01 depletes endogenous BCL6 levels in SuDHL4 cells (high BCL6 expression) and BCL6B levels in KYO1 cells (high BCL6B expression). ALV-05-077-01 can be used for the study of hematological malignancies. | |||||||||||||||||||||
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Keywords
