24394-14-7
Chemical Structure
Phaseic acid
- CAS No.: 24394-14-7
- Formula:C15H20O5
- Molecular Weight:280.32
IUPAC Name: (2Z,4E)-5-((1R,5R,8S)-8-hydroxy-1,5-dimethyl-3-oxo-6-oxabicyclo[3.2.1]octan-8-yl)-3-methylpenta-2,4-dienoic acid
InChIKey: IZGYIFFQBZWOLJ-UUZREKTLSA-N
SMILES: O=C(O)/C=C(C)\C=C\[C@]1(O)[C@]2(C)CC(C[C@@]1(C)OC2)=O
Biological Activity: Phaseic acid is a Abscisic acid terpenoid catabolite that can able to activate a subset of Abscisic acid repectors. Phaseic acid is a plant hormone associated with photosynthesis arrest and abscission. Phaseic acid is the antagonist for NMDA-type glutamate receptor (NMDAR) that inhibits NMDAR currents with an IC50 of 34.37 μM. Phaseic acid reduces intracellular calcium influx, and exhibits neuroprotective effect[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Phaseic acid | 98.76% | Phaseic acid is a Abscisic acid terpenoid catabolite that can able to activate a subset of Abscisic acid repectors. Phaseic acid is a plant hormone associated with photosynthesis arrest and abscission. Phaseic acid is the antagonist for NMDA-type glutamate receptor (NMDAR) that inhibits NMDAR currents with an IC50 of 34.37 μM. Phaseic acid reduces intracellular calcium influx, and exhibits neuroprotective effect. | ||||||||||||||||||||
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Similarity Score 0.82
HY-1168314′-Dihydrophaseic acid -
Similarity Score 0.76
HY-N13503Methylepi-dihydrophaseate -
Similarity Score 0.67
HY-N27838'-Oxo-6-hydroxydihydrophaseic acid -
Similarity Score 0.66
HY-100560RAbscisic acid (Standard) -
Similarity Score 0.66
HY-N2549(±)-Abscisic acid -
Similarity Score 0.66
HY-N2549A(±)-trans-Abscisic acid -
Similarity Score 0.64
HY-1187615,6-Epoxyretinoic acid -
Similarity Score 0.64
HY-1193595,6-Epoxy-13-cis retinoic acid -
Similarity Score 0.58
HY-W653739(+)-Abscisic aldehyde -
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References
- [1]. Pedro L Rodriguez, et al. Abscisic Acid Catabolism Generates Phaseic Acid, a Molecule Able to Activate a Subset of ABA Receptors. Mol Plant. 2016 Nov 7;9(11):1448-1450. [Content Brief]
- [2]. Hou ST, et al., Phaseic Acid, an Endogenous and Reversible Inhibitor of Glutamate Receptors in Mouse Brain. J Biol Chem. 2016 Dec 30;291(53):27007-27022. [Content Brief]
