2452118-54-4
Chemical Structure
VIM-2-IN-1
- CAS No.: 2452118-54-4
- Formula:C12H13IN4O4S
- Molecular Weight:436.23
IUPAC Name: (4-(((4-iodophenyl)sulfonamido)methyl)-1H-1,2,3-triazol-5-yl)methyl acetate
InChIKey: XYPUWRGAZUOXMX-UHFFFAOYSA-N
SMILES: CC(OCC1=C(N=NN1)CNS(=O)(C2=CC=C(C=C2)I)=O)=O
Biological Activity: VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively[1].
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VIM-2-IN-1 | VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively. | |||||||||||||||||||||
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Keywords