2454244-02-9

IRAK4-IN-6 Chemical Structure
2454244-02-9

Chemical Structure

IRAK4-IN-6

  • CAS No.: 2454244-02-9
  • Formula:C25H32N10O2
  • Molecular Weight:504.59

IUPAC Name: methyl 4-((1r,4r)-4-((6-(cyanomethyl)-2-((1-methyl-1H-pyrazol-4-yl)amino)pyrido[3,2-d]pyrimidin-4-yl)amino)cyclohexyl)piperazine-1-carboxylate

InChIKey: RPGMSHCJIWHISY-IRJFHVNHSA-N

SMILES: O=C(N1CCN([C@@H]2CC[C@@H](NC3=C4C(C=CC(CC#N)=N4)=NC(NC5=CN(C)N=C5)=N3)CC2)CC1)OC

Biological Activity: IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma[1].

Cat. No. Product Name Purity Description Pricing
HY-130253
IRAK4-IN-6 99.30% IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma.
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