1. Immunology/Inflammation
    Protein Tyrosine Kinase/RTK
  2. IRAK
  3. IRAK4-IN-6

IRAK4-IN-6 

Cat. No.: HY-130253
Handling Instructions

IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma.

For research use only. We do not sell to patients.

IRAK4-IN-6 Chemical Structure

IRAK4-IN-6 Chemical Structure

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Description

IRAK4-IN-6 is an orally efficacious and selective IRAK4 inhibitor with an IC50 of 4 nM, and targetes MyD88 L265P mutant diffuse large B cell lymphoma[1].

IC50 & Target

IC50: 4 nM (IRAK4)[1]

Molecular Weight

504.59

Formula

C₂₅H₃₂N₁₀O₂

SMILES

O=C(N1CCN([[email protected]@H]2CC[[email protected]@H](NC3=C4C(C=CC(CC#N)=N4)=NC(NC5=CN(C)N=C5)=N3)CC2)CC1)OC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

IRAK4-IN-6IRAKInterleukin-1 receptor associated kinaseIL-1R associated kinaseInhibitorinhibitorinhibit

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IRAK4-IN-6
Cat. No.:
HY-130253
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