2460651-10-7
Chemical Structure
Antitubercular agent-28
- CAS No.: 2460651-10-7
- Formula:C17H14N4O2
- Molecular Weight:306.32
IUPAC Name: N-(2-cyclopropyl-4-oxoquinazolin-3(4H)-yl)isonicotinamide
InChIKey: VYZBEGVYSBLEHZ-UHFFFAOYSA-N
SMILES: O=C(NN1C(C2CC2)=NC3=C(C=CC=C3)C1=O)C4=CC=NC=C4
Biological Activity: Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC50 value of 1.5 µM, an MIC value of 4.5 µM, an IC90 value of 2.5 µM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity[1].
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Antitubercular agent-28 | Antitubercular agent-28 (compound 2) is a potent antitubercular agent with an IC50 value of 1.5 µM, an MIC value of 4.5 µM, an IC90 value of 2.5 µM. Antitubercular agent-28 shows antimycobacterial activity for resistant isolates of Mycobacterium tuberculosis H37Rv. Antitubercular agent-28 shows effective intracellular antimycobacterial activity and low cytotoxicity. | |||||||||||||||||||||
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Keywords
