2465-11-4
2465-11-4
Chemical Structure
Stellasterol
- CAS No.: 2465-11-4
- Formula:C28H46O
- Molecular Weight:398.66
IUPAC Name: (3S,5S,9R,10S,13R,14R,17R)-17-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-10,13-dimethyl-2,3,4,5,6,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol
InChIKey: QOXPZVASXWSKKU-UEIWAABPSA-N
SMILES: C[C@H](C(C)C)/C=C/[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Biological Activity: Stellasterol is a natural product. Stellasterol has high affinity towards Bcl-2 protein (Ki: 118.05 nM). Stellasterol is a weak α-glucosidase inhibitor[1][2].
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Stellasterol | Stellasterol is a natural product. Stellasterol has high affinity towards Bcl-2 protein (Ki: 118.05 nM). Stellasterol is a weak α-glucosidase inhibitor. | |||||||||||||||||||||
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References
- [1]. Lau MF, et al. In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cells. Biotechnol Appl Biochem. 2021 Aug;68(4):902-917. [Content Brief]
- [2]. Krisyanti Budipramana, et al. An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from Ganoderma austral. Sci. Pharm. 2019, 87(3). 21.
