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Cat. No.: HY-N1218

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Stellasterol

Stellasterol is a natural product. Stellasterol has high affinity towards Bcl-2 protein (K_i: 118.05 nM). Stellasterol is a weak α-glucosidase inhibitor.

For research use only. We do not sell to patients.

CAS No.: 2465-11-4
Formula: C₂₈H₄₆O
Molecular Weight:398.66

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Stellasterol Chemical Structure

CAS No.: 2465-11-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Stellasterol is a natural product. Stellasterol has high affinity towards Bcl-2 protein (K_i: 118.05 nM). Stellasterol is a weak α-glucosidase inhibitor^[1]^[2].

All Bcl-2 Family Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEp-2	IC₅₀	50.5 μM Compound: 7	Antiviral activity against Parainfluenza virus type 3 infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay Antiviral activity against Parainfluenza virus type 3 infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay	[PMID: 19267453]
HEp-2	IC₅₀	50.5 μM Compound: 7	Antiviral activity against Respiratory syncytial virus infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay Antiviral activity against Respiratory syncytial virus infected in human Hep2 cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay	[PMID: 19267453]
MDCK	IC₅₀	0.03 μg/mL Compound: 7	Antiviral activity against herpes simplex virus 1 infected in MDCK cells Antiviral activity against herpes simplex virus 1 infected in MDCK cells	[PMID: 16378363]
MDCK	IC₅₀	0.78 μg/mL Compound: 7	Antiviral activity against influenza A virus infected in MDCK cells Antiviral activity against influenza A virus infected in MDCK cells	[PMID: 16378363]
MDCK	IC₅₀	202.3 μM Compound: 7	Antiviral activity against Influenza A virus infected in MDCK cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay Antiviral activity against Influenza A virus infected in MDCK cells assessed as inhibition of virus-induced cytopathogenic effect by plaque reduction assay	[PMID: 19267453]

Chemical Information

CAS No. 2465-11-4
Molecular Weight 398.66
Formula C₂₈H₄₆O
SMILES

C[C@H](C(C)C)/C=C/[C@@H](C)[C@H]1CC[C@@]2([H])C3=CC[C@@]4([H])C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Structure Classification
- Steroids
Initial Source
- Animals
starfish
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lau MF, et al. In vitro and in silico anticancer evaluation of a medicinal mushroom, Ganoderma neo-japonicum Imazeki, against human colonic carcinoma cells. Biotechnol Appl Biochem. 2021 Aug;68(4):902-917. [Content Brief]

[2]. Krisyanti Budipramana, et al. An Integrated In Silico and In Vitro Assays of Dipeptidyl Peptidase-4 and α-Glucosidase Inhibition by Stellasterol from Ganoderma austral. Sci. Pharm. 2019, 87(3). 21.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Stellasterol

High-Throughput Bioactive Compound Library

All Bcl-2 Family Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Stellasterol Related Classifications

HY-N1218 Related Classifications