2490154-44-2
2490154-44-2
Chemical Structure
Anti-MRSA agent 5
- CAS No.: 2490154-44-2
- Formula:C25H22N4O4
- Molecular Weight:442.47
IUPAC Name: 1-cyclopropyl-7-((4-(3,4-dimethylphenoxy)pyrimidin-2-yl)amino)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
InChIKey: LVWQTFGGIKODJA-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C2CC2)C3=C(C=CC(NC4=NC=CC(OC5=CC=C(C)C(C)=C5)=N4)=C3)C1=O)O
Biological Activity: Anti-MRSA agent 5 (B14) is a potent MRSAagent with MIC50 values of 0.38 μg/mL and has low hERG activity with an IC50 values of >40 μM. Anti-MRSA agent 5 (B14) also has low cytotoxicity to mammal cells and unlikely to acquire bacterial resistance[1].
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Anti-MRSA agent 5 | Anti-MRSA agent 5 (B14) is a potent MRSAagent with MIC50 values of 0.38 μg/mL and has low hERG activity with an IC50 values of >40 μM. Anti-MRSA agent 5 (B14) also has low cytotoxicity to mammal cells and unlikely to acquire bacterial resistance. | |||||||||||||||||||||
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References
Keywords
