2490538-41-3
2490538-41-3
Chemical Structure
FTase-IN-1
- CAS No.: 2490538-41-3
- Formula:C23H16N2O2S
- Molecular Weight:384.45
IUPAC Name: 1-(1-(10H-phenothiazine-3-carbonyl)indolizin-3-yl)ethan-1-one
InChIKey: QPASHDWXDWXGRX-UHFFFAOYSA-N
SMILES: CC(C1=CC(C(C2=CC=C3NC4=C(C=CC=C4)SC3=C2)=O)=C5C=CC=CN15)=O
Biological Activity: FTase-IN-1 (compound 17a) is a potent and specific inhibitor of fanesyl transferase (FTase) with an IC50 of 0.35 μM. FTase-IN-1 displays cytotoxicity potential and antitumor activity[1].
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FTase-IN-1 | FTase-IN-1 (compound 17a) is a potent and specific inhibitor of fanesyl transferase (FTase) with an IC50 of 0.35 μM. FTase-IN-1 displays cytotoxicity potential and antitumor activity. | |||||||||||||||||||||
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References
Keywords
