2491-17-0
Chemical Structure
CME-carbodiimide
- CAS No.: 2491-17-0
- Formula:C21H33N3O4S
- Molecular Weight:423.57
IUPAC Name: 4-(2-(((cyclohexylimino)methylene)amino)ethyl)-4-methylmorpholin-4-ium 4-methylbenzenesulfonate
InChIKey: GBCAVSYHPPARHX-UHFFFAOYSA-M
SMILES: C[N+]1(CCN=C=NC2CCCCC2)CCOCC1.O=S(C3=CC=C(C)C=C3)([O-])=O
Biological Activity: CME-carbodiimide is a nucleic acid modification reagent. CME-carbodiimide reacts specifically with uracil and guanine residues of RNA, as well as guanine and thymine residues of denatured DNA; it does not react with native DNA. Modification of DNA by CME-carbodiimide inhibits phosphodiester bond cleavage or DNA hydrolysis mediated by pancreatic ribonuclease, snake venom phosphodiesterase and deoxyribonuclease[1].
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CME-carbodiimide | 98.0% | CME-carbodiimide is a nucleic acid modification reagent. CME-carbodiimide reacts specifically with uracil and guanine residues of RNA, as well as guanine and thymine residues of denatured DNA; it does not react with native DNA. Modification of DNA by CME-carbodiimide inhibits phosphodiester bond cleavage or DNA hydrolysis mediated by pancreatic ribonuclease, snake venom phosphodiesterase and deoxyribonuclease. | ||||||||||||||||||||
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