2494010-63-6
2494010-63-6
Chemical Structure
ERK-IN-7
- CAS No.: 2494010-63-6
- Formula:C22H20ClN7O2
- Molecular Weight:449.89
IUPAC Name: (S)-2-(1-(3-chlorophenyl)-2-hydroxyethyl)-6-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)-1,2-dihydro-3H-pyrrolo[1,2-c]imidazol-3-one
InChIKey: UNXNCWQFELCKHX-LJQANCHMSA-N
SMILES: O=C1N2C(CN1[C@@H](C3=CC(Cl)=CC=C3)CO)=CC(C4=NC(NC5=CC=NN5C)=NC=C4)=C2
Biological Activity: ERK-IN-7 (Example 10), an analogue of SHR2415 (HY-151367), is a potent ERK inhibitor with IC50 of 5 nM and 7 nM against ERK1 and ERK2, respectively[1].
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ERK-IN-7 | ERK-IN-7 (Example 10), an analogue of SHR2415 (HY-151367), is a potent ERK inhibitor with IC50 of 5 nM and 7 nM against ERK1 and ERK2, respectively. | |||||||||||||||||||||
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References
Keywords
