2518100-58-6
2518100-58-6
Chemical Structure
Avobenzone-d3
- CAS No.: 2518100-58-6
- Formula:C20H19D3O3
- Molecular Weight:313.41
IUPAC Name: 1-(4-(tert-butyl)phenyl)-3-(4-(methoxy-d3)phenyl)propane-1,3-dione
InChIKey: XNEFYCZVKIDDMS-GKOSEXJESA-N
SMILES: O=C(C1=CC=C(C=C1)OC([2H])([2H])[2H])CC(C2=CC=C(C=C2)C(C)(C)C)=O
Biological Activity: Avobenzone-d3 is deuterium labeled Avobenzone. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist[1][2][3].
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Avobenzone-d3 | 98.0% | Avobenzone-d3 is deuterium labeled Avobenzone. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist. | ||||||||||||||||||||
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Avobenzone (Standard) | 98.55% | Avobenzone (Standard) is the analytical standard of Avobenzone. This product is intended for research and analytical applications. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist. | ||||||||||||||||||||
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Avobenzone-13C,d3 | 99.9% | Avobenzone-13C,d3 is the 13C- and deuterium labeled Avobenzone. Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist. | ||||||||||||||||||||
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Avobenzone | 98.0% | Avobenzone, a dibenzoylmethane compound, is one of the most widely used filters in sunscreens for skin photoprotection in the UVA band. Avobenzone is an endocrine disruptor that directly binds to estrogen receptor β and acts as an estrogen agonist. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
- [2]. Kojić M, et al. A new insight into the photochemistry of avobenzone in gas phase and acetonitrile from ab initio calculations. Phys Chem Chem Phys. 2016;18(32):22168-22178. [Content Brief]
- [3]. Ahn S, An S, et al. A long-wave UVA filter avobenzone induces obesogenic phenotypes in normal human epidermal keratinocytes and mesenchymal stem cells. Arch Toxicol. 2019;93(7):1903-1915. [Content Brief]
