2566497-96-7
Chemical Structure
Antitumor agent-68
- CAS No.: 2566497-96-7
- Formula:C17H11NO2
- Molecular Weight:261.27
IUPAC Name: 4-chloro-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
InChIKey: VLGSRCGJYOURLG-UHFFFAOYSA-N
SMILES: O=C(OC1=CC2=C(NC=C2)C=C1)C#CC3=CC=CC=C3
Biological Activity: Antitumor agent-68 is a potent tubulin inhibitor. Antitumor agent-68 shows potent anticancer activity with IC50s of 3.6 and 3.8 μM for HeLa and MCF-7 cells, respectively. Antitumor agent-68 exhibits good scavenging activity of ROS and DPPH radical in a dose-dependent manner[1]. Antitumor agent-68 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Antitumor agent-68 | Antitumor agent-68 is a potent tubulin inhibitor. Antitumor agent-68 shows potent anticancer activity with IC50s of 3.6 and 3.8 μM for HeLa and MCF-7 cells, respectively. Antitumor agent-68 exhibits good scavenging activity of ROS and DPPH radical in a dose-dependent manner. Antitumor agent-68 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | |||||||||||||||||||||
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