2568273-82-3

PROTAC SMARCA2/4 degrader-29 Chemical Structure
2568273-82-3

Chemical Structure

PROTAC SMARCA2/4 degrader-29

  • CAS No.: 2568273-82-3
  • Formula:C44H51N11O4
  • Molecular Weight:797.95

InChIKey: PUBFSJSCCCSWBL-PNTLQCOASA-N

SMILES: O=C1N(C2C(NC(CC2)=O)=O)C3=CC=C([C@@H]4CC[C@H](N5CCC(C6=NC=CC(N7C8CN(C9=C(N)N=NC(C%10=C(C=CC=C%10)O)=C9)CC7CC8)=N6)CC5)CC4)C=C3N1C

Biological Activity: PROTAC SMARCA2/4-degrader-29 (Compound I-279) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-29 degrades SMARCA2 in A549 with DC50 <100 nM, degrades SMARCA4 in MV411 with DC50 <100 nM[1].

Cat. No. Product Name Purity Description Pricing
HY-162743 		PROTAC SMARCA2/4 degrader-29 PROTAC SMARCA2/4-degrader-29 (Compound I-279) is a PROTAC degrader for catalytic subunit of the SWI/SNF complex SMARCA2 and SMARCA4. PROTAC SMARCA2/4-degrader-29 degrades SMARCA2 in A549 with DC50 <100 nM, degrades SMARCA4 in MV411 with DC50 <100 nM.
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