258278-64-7
Chemical Structure
SE 175
- CAS No.: 258278-64-7
- Formula:C16H13NO6S
- Molecular Weight:347.34
IUPAC Name: methyl 2-((4-((nitrooxy)methyl)benzoyl)thio)benzoate
InChIKey: JDIVRBDMTYQVOK-UHFFFAOYSA-N
SMILES: O=C(OC)C1=CC=CC=C1SC(C2=CC=C(CO[N+]([O-])=O)C=C2)=O
Biological Activity: SE 175 is an organic nitrate compound that acts as an NO donor in vivo following reductive transformation of the nitrate group to nitric oxide. SE 175 stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC50 of 0.20 µM[1].
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SE 175 | SE 175 is an organic nitrate compound that acts as an NO donor in vivo following reductive transformation of the nitrate group to nitric oxide. SE 175 stimulates endothelial soluble guanylate cyclase and induces aortic vasorelaxation with an EC50 of 0.20 µM. | |||||||||||||||||||||
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Keywords