2589926-27-0
Chemical Structure
Ulefnersen sodium
Synonym(s): ION-363 sodium
- CAS No.: 2589926-27-0
- Formula:C230H302N68O126P19S13Na19
- Molecular Weight:7060 (free acid)
SMILES: [Ulefnersen (sodium)]
Biological Activity: Ulefnersen sodium (ION363) is an Antisense Oligonucleotide (ASO) directed against the 6th intron of the fused-in sarcoma (FUS) transcript to silence FUS in a non-allele-specific manner. Ulefnersen sodium can reduce postnatal levels of FUS protein in the brain and spinal cord in disease-relevant mouse model of ALS-FUS , delaying motor neuron degeneration. Ulefnersen sodium can be used in the research of Amyotrophic Lateral Sclerosis (ALS) [1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ulefnersen sodium | 98.47% | Ulefnersen sodium (ION363) is an Antisense Oligonucleotide (ASO) directed against the 6th intron of the fused-in sarcoma (FUS) transcript to silence FUS in a non-allele-specific manner. Ulefnersen sodium can reduce postnatal levels of FUS protein in the brain and spinal cord in disease-relevant mouse model of ALS-FUS , delaying motor neuron degeneration. Ulefnersen sodium can be used in the research of Amyotrophic Lateral Sclerosis (ALS) . | ||||||||||||||||||||
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Keywords
