2595314-46-6
2595314-46-6
Chemical Structure
WEHI-9625
- CAS No.: 2595314-46-6
- Formula:C34H27NO5S2
- Molecular Weight:593.71
IUPAC Name: 7-(2-(4-methoxybenzoyl)phenyl)-N-(4-methylbenzyl)-4H-thieno[3,2-c]thiochromene-2-carboxamide 5,5-dioxide
InChIKey: DQVRUUKJUZNKSW-UHFFFAOYSA-N
SMILES: O=C(C(S1)=CC(CS2(=O)=O)=C1C3=C2C=C(C4=CC=CC=C4C(C5=CC=C(OC)C=C5)=O)C=C3)NCC6=CC=C(C)C=C6
Biological Activity: WEHI-9625 is a tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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WEHI-9625 | 99.46% | WEHI-9625 is a tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX. | ||||||||||||||||||||
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