2597056-86-3
2597056-86-3
Chemical Structure
PD-L1-IN-4
- CAS No.: 2597056-86-3
- Formula:C38H40ClFN4O8
- Molecular Weight:735.20
InChIKey: CVHGLSHXHMFDJX-UUWRZZSWSA-N
SMILES: FC1=C(C=CC=C1C2=CC(OCCCN3CCC(CC3)O)=CC=C2)COC4=CC(OCC5=CC6=NON=C6C=C5)=C(C=C4Cl)CN[C@@H](C(O)=O)CO
Biological Activity: PD-L1-IN-4 (Compound X18) is an orally active PD-L1 inhibitor that exhibits remarkable inhibitory activity against the PD-1/PD-L1 interaction (IC50 = 1.3 nM) and enhances PD-L1 inhibitory effect on T cells (EC50 = 152.8 nM). PD-L1-IN-4 can be used for the research of cancer[1].
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PD-L1-IN-4 | PD-L1-IN-4 (Compound X18) is an orally active PD-L1 inhibitor that exhibits remarkable inhibitory activity against the PD-1/PD-L1 interaction (IC50 = 1.3 nM) and enhances PD-L1 inhibitory effect on T cells (EC50 = 152.8 nM). PD-L1-IN-4 can be used for the research of cancer. | |||||||||||||||||||||
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References
Keywords
