259886-51-6
![Cucurbit[8]uril Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-103689.gif "Cucurbit[8]uril Chemical Structure")
Chemical Structure
Cucurbit[8]uril
- CAS No.: 259886-51-6
- Formula:C48H48N32O16
- Molecular Weight:1329.10
InChIKey: CONWISUOKHSUDR-LBCLZKRDSA-N
SMILES: O=C1N(CN(C2=O)[C@]([C@@]3([H])N2CN(C4=O)[C@]([C@@]5([H])N4CN(C6=O)[C@]([C@@]7([H])N6CN8[C@]9([H])N(C%10=O)CN%117)([H])N(C%11=O)CN%125)([H])N(C%12=O)CN3C%13=O)([H])N%13CN%14%15)[C@]%14([H])[C@]%16([H])N1CN(C%17=O)[C@@]([C@]%18([H])N%17CN(C%19=O)[C@@]([C@]%20([H])N%19CN(C%21=O)[C@@]([C@]%22([H])N%21CN%23C8=O)([H])N(C(N%22CN%10[C@]%239[H])=O)CN%24%20)([H])N(C%24=O)CN%18C%25=O)([H])N%25CN%16C%15=O
Biological Activity: Cucurbit[8]uril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbit[8]uril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbit[8]uril can induce energy transfer [1][2].
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Cucurbit[8]uril | 98.0% | Cucurbituril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbituril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbituril can induce energy transfer . | ||||||||||||||||||||
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Cucurbit[8]uril (Standard) | ≥98% | Cucurbituril (Standard) is the analytical standard of Cucurbituril (HY-103689). This product is intended for research and analytical applications. Cucurbituril is a potent, low toxicity and orally active supramolecular inducer of protein heterodimerization. Cucurbituril induces heterodimerization of methylviologen and naphthalene functionalized proteins. Cucurbituril can induce energy transfer . | ||||||||||||||||||||
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References
- [1]. Uhlenheuer DA, et al. Cucurbit[8]uril induced heterodimerization of methylviologen and naphthalene functionalized proteins. Chem Commun (Camb). 2011;47(24):6798-6800. [Content Brief]
- [2]. Uzunova VD, et al. Toxicity of cucurbit[7]uril and cucurbit[8]uril: an exploratory in vitro and in vivo study. Org Biomol Chem. 2010;8(9):2037-2042. [Content Brief]
