2634811-35-9
Chemical Structure
ZSQ836
- No. CAS: 2634811-35-9
- Formula:C27H28AsClN6OS2
- Molecular Weight:627.06
InChIKey: SHJIQFGWCILYIF-HXUWFJFHSA-N
SMILES: ClC1=CN=C(N[C@H]2CN(CCC2)CC(NC3=CC=C([As]4SCCS4)C=C3)=O)N=C1C5=CNC6=CC=CC=C56
Biological Activity: ZSQ836 is an orally active dual covalent inhibitor of CDK12/CDK13, with an EC50 value of 32 nM against CDK12. ZSQ836 can induce apoptosis and exhibit anticancer activity in vivo. ZSQ836 can be used in the study of ovarian cancer[1].
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ZSQ836 | ZSQ836 is an orally active dual covalent inhibitor of CDK12/CDK13, with an EC50 value of 32 nM against CDK12. ZSQ836 can induce apoptosis and exhibit anticancer activity in vivo. ZSQ836 can be used in the study of ovarian cancer. | |||||||||||||||||||||
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Keywords