2647975-06-0
Chemical Structure
SSAO/VAP-1 inhibitor 1
- CAS No.: 2647975-06-0
- Formula:C16H22ClFN2O3
- Molecular Weight:344.81
IUPAC Name: (E)-2-(3-amino-1-fluoroprop-1-en-2-yl)-N-(tert-butyl)-2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamide hydrochloride
InChIKey: HHWSXSSYAXVJRQ-RVDQCCQOSA-N
SMILES: O=C(C1=CC=C(OC(/C(CN)=C/F)CO2)C2=C1)NC(C)(C)C.[H]Cl
Biological Activity: SSAO/VAP-1 inhibitor 1 is a potent inhibitor of SSAO/VAP-1. SSAO/VAP-1 promotes the transfer of Glucose transport 4 (GLUT 4) from adipocytes to the cell membrane, thereby regulating glucose transport. In endothelial cells, SSAO/VAP-1 can mediate the adhesion and exudation of leukocytes and endothelial cells, and participate in inflammatory responses. SSAO/VAP-1 inhibitor 1 has the potential for the research of inflammation and/or inflammation-related disease or diabetes and/or diabetes-related disease (extracted from patent WO2021102774A1, compound E3)[1].
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SSAO/VAP-1 inhibitor 1 | SSAO/VAP-1 inhibitor 1 is a potent inhibitor of SSAO/VAP-1. SSAO/VAP-1 promotes the transfer of Glucose transport 4 (GLUT 4) from adipocytes to the cell membrane, thereby regulating glucose transport. In endothelial cells, SSAO/VAP-1 can mediate the adhesion and exudation of leukocytes and endothelial cells, and participate in inflammatory responses. SSAO/VAP-1 inhibitor 1 has the potential for the research of inflammation and/or inflammation-related disease or diabetes and/or diabetes-related disease (extracted from patent WO2021102774A1, compound E3). | |||||||||||||||||||||
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Keywords
