2653338-59-9
2653338-59-9
Chemical Structure
Thalidomide-4-O-C12-Br
- CAS No.: 2653338-59-9
- Formula:C25H33BrN2O5
- Molecular Weight:521.44
InChIKey: QXENSGPXEHNSGK-UHFFFAOYSA-N
SMILES: BrCCCCCCCCCCCCOC1=C(C2=CC=C1)C(N(C2=O)C3CCC(NC3=O)=O)=O
Biological Activity: Thalidomide-4-O-C12-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C12-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-24 (HY-181325)[1].
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Thalidomide-4-O-C12-Br | Thalidomide-4-O-C12-Br is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based CRBN ligand and a linker used in PROTAC technology. Thalidomide-4-O-C12-Br can be connected to the ligand for protein by a linker to form PROTAC EZH2 Degrader-24 (HY-181325). | |||||||||||||||||||||
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References
Keywords
