2653338-70-4
Chemical Structure
PROTAC EZH2 Degrader-27
- CAS No.: 2653338-70-4
- Formula:C53H65N7O8
- Molecular Weight:928.13
InChIKey: SYBFJJUKUKOTOQ-UHFFFAOYSA-N
SMILES: CCN(C1CCOCC1)C2=CC(C3=CC=C(C=C3)CN4CCN(CC4)CCCCCCOC5=C(C6=CC=C5)C(N(C6=O)C7CCC(NC7=O)=O)=O)=CC(C(NCC8=C(C=C(NC8=O)C)C)=O)=C2C
Biological Activity: PROTAC EZH2 Degrader-27 is a EZH2 PROTAC inhibitor with an IC50 of 4.00 nM against EZH2. PROTAC EZH2 Degrader-27 inhibits methyltransferase activity by interacting with the SET domain of EZH2[1].
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PROTAC EZH2 Degrader-27 | PROTAC EZH2 Degrader-27 is a EZH2 PROTAC inhibitor with an IC50 of 4.00 nM against EZH2. PROTAC EZH2 Degrader-27 inhibits methyltransferase activity by interacting with the SET domain of EZH2. | |||||||||||||||||||||
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Keywords