2654003-64-0
2654003-64-0
Chemical Structure
CDK7-IN-8
- CAS No.: 2654003-64-0
- Formula:C25H38N8O3
- Molecular Weight:498.62
IUPAC Name: (S,E)-1-(4-(dimethylamino)but-2-enoyl)pyrrolidin-3-yl 4-((8-isopropyl-2-methylpyrazolo[1,5-a][1,3,5]triazin-4-yl)amino)piperidine-1-carboxylate
InChIKey: HXZSBIHJXCUDFN-YJJPMGAVSA-N
SMILES: CC(C1=C2N(N=C1)C(NC3CCN(CC3)C(O[C@@H]4CN(CC4)C(/C=C/CN(C)C)=O)=O)=NC(C)=N2)C
Biological Activity: CDK7-IN-8 is a potent CDK7 inhibitor with IC50 of 54.29 nM. CDK7-IN-8 has inhibitory effect on certain cancer cells and in vivo tumor models[1].
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CDK7-IN-8 | CDK7-IN-8 is a potent CDK7 inhibitor with IC50 of 54.29 nM. CDK7-IN-8 has inhibitory effect on certain cancer cells and in vivo tumor models. | |||||||||||||||||||||
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References
Keywords
