2654741-56-5
2654741-56-5
Chemical Structure
SOS1-IN-12
- CAS No.: 2654741-56-5
- Formula:C23H26F3N5
- Molecular Weight:429.48
IUPAC Name: (R)-4-methyl-N-(1-(2-methyl-3-(trifluoromethyl)phenyl)ethyl)-7-(piperazin-1-yl)phthalazin-1-amine
InChIKey: MJSKXOIIHARCLW-OAHLLOKOSA-N
SMILES: CC1=NN=C(C2=CC(N3CCNCC3)=CC=C21)N[C@@H](C4=CC=CC(C(F)(F)F)=C4C)C
Biological Activity: SOS1-IN-12 is a potent son of sevenless homolog 1 (SOS1) inhibitor with a Ki of 0.11 nM for SOS1 and an IC50 of 47 nM for pERK. SOS1-IN-13 can be used for researching anticancer[1].
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SOS1-IN-12 | SOS1-IN-12 is a potent son of sevenless homolog 1 (SOS1) inhibitor with a Ki of 0.11 nM for SOS1 and an IC50 of 47 nM for pERK. SOS1-IN-13 can be used for researching anticancer. | |||||||||||||||||||||
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References
Keywords
