SOS1-IN-12
SOS1-IN-12 is a potent son of sevenless homolog 1 (SOS1) inhibitor with a Ki of 0.11 nM for SOS1 and an IC50 of 47 nM for pERK. SOS1-IN-13 can be used for researching anticancer.
For research use only. We do not sell to patients.
- CAS No.: 2654741-56-5
- Formula: C23H26F3N5
- Molecular Weight:429.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MKN-1 | IC50 |
46 nM
Compound: 18
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Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured after 48 hrs by 48 hrs by CCK-8 assay
Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured after 48 hrs by 48 hrs by CCK-8 assay
|
[PMID: 37542991] |
| MKN-1 | IC50 |
46 nM
Compound: 18
|
Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured for 48 hrs by CCK-8 assay
Antiproliferative activity against human MKN-1 cells assessed as reduction in cell viability measured for 48 hrs by CCK-8 assay
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[PMID: 38430853] |
Chemical Information
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CAS No. 2654741-56-5
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Molecular Weight 429.48
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Formula C23H26F3N5
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SMILES
CC1=NN=C(C2=CC(N3CCNCC3)=CC=C21)N[C@@H](C4=CC=CC(C(F)(F)F)=C4C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SOS1-IN-12 Related Classifications
HY-144965 Related Classifications
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